A Precision, Systems-Based Approach to Complex Health
When health feels confusing, overwhelming, or stuck, guessing doesn’t work.
The INSIGHT™ Method is Dr. Angie Martinez’s proprietary framework for turning complex symptoms and lab data into a clear, sequenced plan—so your body can finally respond.
INSIGHT™ is a physician-led, data-driven system that maps your symptoms, history, and biomarkers across core biological systems—then prioritizes care in the right order to create measurable momentum.
It is designed for people with:
Fatigue that doesn’t match their labs
Inflammation or immune reactivity
Hormone disruption
Gut instability
Metabolic resistance
Brain fog or cognitive decline
Complex or overlapping conditions
This is not protocol-based care.
It is sequenced, systems-based strategy.

Why Traditional Approaches Fall Short
Most healthcare models focus on:
Isolated diagnoses
Single lab markers
Symptom suppression
Trend-driven protocols
But complex health issues are rarely one problem.
They are patterns across systems:
Inflammation → metabolism → gut → hormones → nervous system → detox capacity.
If we treat them out of order, progress stalls.
INSIGHT™ exists to answer:
What matters most right now—and what should wait?
We don’t assume which system is the problem. We measure, map, and prioritize.
Each letter represents a foundational biological system:
The INSIGHT™ Pillars
I – Inflammation & Infections
Immune signaling, inflammatory load, and hidden drivers of systemic stress.
N – Nutrients
Micronutrient status, absorption, mitochondrial fuel, and cellular energy.
S – Stress Chemistry & Sleep
Cortisol rhythm, nervous system tone, and restorative recovery patterns.
I – Insulin & Metabolism
Glucose regulation, metabolic flexibility, cardiometabolic risk.
G – Gut & Microbiome
Digestive integrity, microbial balance, permeability patterns.
H – Hormone Harmony
Thyroid, sex hormones, adrenal regulation, cycle-aware mapping.
T – Toxins & Detox Load
Environmental load, detox pathways, liver function, resilience.

At the center of the method is your living INSIGHT™ Health Profile.
This profile:
Integrates intake data, labs, vitals, and functional metrics
Tracks trends over time—not snapshots
Highlights wins and health assets
Flags weaker links still needing support
It becomes your health résumé—showing where you started, what changed, and what we optimize next.
Progress is visible. Care is measurable.

Step 1
We gather advanced labs, symptom history, timeline mapping, and functional measures (when appropriate).
Examples may include:
→ Body composition
→ VO₂ max
→ Grip strength
→ Nitric oxide
→ CGM
→ Standard and specialty labs
Testing is chosen intentionally—not all at once.
Step 2
We prioritize care in order.
Often that means:
→ Stabilizing immune signaling
→ Supporting metabolic energy
→ Calming inflammatory load
→ Restoring gut integrity
Only after the foundation is stable do we refine hormones, longevity, or performance strategies.
Right system. Right time.
Step 3
Follow-ups are structured.
We reassess:
→ Symptoms
→ Biomarkers
→ Response patterns
If something isn’t moving, we adjust.
INSIGHT™ is adaptable—not rigid.
"We integrate intake data, vital signs, and over 100 biomarkers—drawing from PCP labs, body composition, VO₂ max, handgrip strength, nitric oxide, CGM, ketones, blood, urine, and saliva—to translate your data into a clear systems-based story."

Dr. Angie — Founder, Root Cause Medicine
Built for complex fatigue, chronic inflammation, auto-immune overlap, perimenopause transitions, and "mystery" syndromes that don’t fit neatly in a single diagnosis.

What Makes INSIGHT™ Different From Other Functional Medicine Programs?
Physician-led medical oversight
Systems-based rather than protocol-driven
Objective biomarker tracking
Sequenced care
Measurable progress
Long-term resilience focus
We don’t chase trends. We evaluate physiology.
Every recommendation answers:
→ Does this make biological sense?
→ Is it sequenced correctly?
→ Can we monitor and adjust it?
The method works best for patients who:
Feel stuck despite previous testing or treatment
Are ready for structured follow-up
Want measurable progress—not quick fixes
Understand that complex health takes sequencing
Are open to collaboration and accountability
It may not be a fit if you’re looking for:
One-time lab interpretation only
Supplement lists without follow-up
Rapid, cosmetic-only changes
INSIGHT™ is built for durable change.


Patients commonly experience:
More stable energy
Reduced inflammatory reactivity
Improved metabolic flexibility
Better hormone rhythm
Clearer cognition
Greater sleep consistency
Stronger resilience under stress
The goal isn’t perfection.
It’s raising your baseline so your body has more capacity.
INSIGHT™ is the framework behind:

Stabilize & Reset
Stabilize core systems, identify root causes, and build momentum using INSIGHT™ for complex or stalled health.

Maintain & Refine
Protect gains, refine care, and adapt your plan with ongoing oversight as biology, stress, and goals change!

Optimize & Longevity
Expand capacity, optimize performance, and protect healthspan using precision strategies for longevity resil.
Every level of care builds on this structure.
* Individual results vary. Testimonials reflect personal experiences and are not guarantees of outcome.
“Connected the dots after years of frustration”
“Dr. Martinez really listened to my concerns about my son’s health, connected the dots, and identified what was affecting him. After years of frustration with other providers, she gave us clear insights and a plan of action.”
— Bethany T
“Root-cause answers for fatigue and perimenopause”
I was significantly fatigued and disheartened after trying multiple approaches. With step-by-step lab work and clear interventions, Dr. Martinez helped uncover the root of my exhaustion—and has supported me through perimenopause and stress so I can truly thrive.
— Marissa V
“Life-changing progress in 6 weeks”
“In only a month and a half, Dr. Angie completely changed my life for the better after I’d been passed around for gut issues, inflammation, histamine problems, and brain fog. Her systems and clear, concise education helped me thrive—this was the best investment I’ve made in myself.”
— Katie K
If you’re tired of guessing and want a structured, measurable approach, the next step is a Discovery Call.
We’ll review:
→ Your history
→ What you’ve tried
→ Your goals
→ Whether INSIGHT™ is the right entry point
Currently accepting a limited number of new patients for 2026. Virtual care available in select states.






The INSIGHT™ Health Profile is Dr. Angie Martinez’s proprietary system for turning complex health data into a clear roadmap.
INSIGHT™ maps symptoms, history, and labs across seven foundational systems:
• I – Inflammation & Infections
• N – Nutrients
• S – Stress Chemistry & Sleep
• I – Insulin & Metabolism
• G – Gut Health
• H – Hormones
• T – Toxins & Toxic Load
Over time, your profile becomes a living record of progress—your “health résumé”—showing where you started, what changed, and what we optimize next.
INSIGHT™ Methodology is the step-by-step strategy behind the Health Profile.
We prioritize care in sequence—often stabilizing immune signaling, gut integrity, metabolic energy, and inflammatory load first—then refining hormones, detox capacity, performance, and prevention as your foundation strengthens.
It’s structured, measurable, and adaptable. If your body isn’t responding as expected, we reassess, refine, and adjust using real feedback from symptoms and biomarkers.
The wellness world is loud, and not all of it is grounded in physiology or clinical reasoning. At RootCause, we don’t follow trends—we evaluate data.
Dr. Angie Martinez brings 20+ years of clinical experience bridging conventional training with advanced functional medicine. That matters for safety, clarity, and results.
We evaluate interventions by asking:
• Does it make physiological sense?
• What is the risk-to-benefit ratio for this person?
• Can it be monitored and adjusted using objective markers?
• Do outcomes hold up in real patients over time?
We draw from peer-reviewed research, advanced clinical education, and real-world outcomes—staying current through ongoing training (A4M, menopause-focused education, and other institutes).
Functional Medicine 3.0 often begins where standard care stops—especially when symptoms are real but labs look “normal.”
We start with a strong foundation of conventional biomarkers mapped across INSIGHT™ systems, and when appropriate add tools such as:
• InBody™ body composition analysis
• CGM (continuous glucose monitoring)
• Nitric oxide and ketone testing
• Grip strength and functional measures
• PNOĒ VO₂ max and ventilatory/cardiopulmonary testing
• Mood/cognitive screening when appropriate
• Specialty labs (stool, hormone, immune/autoimmune, toxins/biotoxins, infections)
We don’t test to collect information. We test to create clarity—then turn it into priorities and action.
We don’t test everything at once—and we don’t guess.
Labs are chosen based on:
• Symptoms, history, and goals
• Which systems need clarity first
• What will change clinical decisions
• Cost-to-benefit and timing
Testing is sequenced to maximize ROI and avoid overwhelm.
Bring them.
Your previous labs are part of your health story and often help us spot patterns over time. We review what you already have, use what’s still relevant, and avoid repeating what doesn’t need to be repeated.
You don’t need new labs to start with us. We meet you where you are in your data, then recommend only what adds leverage.
© 2026 Root Cause Medicine, 8790 Ralston Road, Arvada, CO, 80002
Phone: (720) 290-5569 | Email: [email protected]